Disposition of methylenedioxymethamphetamine and three metabolites in the brains of different rat strains and their possible roles in acute serotonin depletionCHU, T; KUMAGAI, Y; DISTEFANO, E. W et al.Biochemical pharmacology. 1996, Vol 51, Num 6, pp 789-796, issn 0006-2952Article

A pharmacokinetic analysis of 3,4-methylenedioxymethamphetamine effects on monoamine concentrations in brain dialysatesHIRAMATSU, M; DISTEFANO, E; CHANG, A. S et al.European journal of pharmacology. 1991, Vol 204, Num 2, pp 135-140, issn 0014-2999Article

Pharmacokinetic and pharmacodynamic properties of some phencyclidine analogs in ratsCHO, A. K; HIRAMATSU, M; SCHMITZ, D. A et al.Pharmacology, biochemistry and behavior. 1991, Vol 39, Num 4, pp 947-953, issn 0091-3057Article

Stereochemical differences in the metabolism of 3,4-methylenedioxymethamphetamine in vivo and in vitro : a pharmacokinetic analysisCHO, A. K; HIRAMATSU, M; DISTEFANO, E. W et al.Drug metabolism and disposition. 1990, Vol 18, Num 5, pp 686-691, issn 0090-9556, 6 p.Article

³H-Xylamine binds to presynaptic rat striatal membranesCUSHING, S. D; HOWARD-BUTCHER, S; GAZZARA, R. A et al.Life sciences (1973). 1986, Vol 38, Num 19, pp 1715-1721, issn 0024-3205Article

Ice : a new dosage form of an old drugCHO, A. K.Science (Washington, D.C.). 1990, Vol 249, Num 4969, pp 631-634, issn 0036-8075, 4 p.Article

Major role of the CYP2C isozymes in deamination of amphetamine and benzphetamine : evidence for the quinidine-specific inhibition of the reactions catalysed by rabbit enzymeSHIIYAMA, S; SOEJIMA-OHKUMA, T; HONDA, S et al.Xenobiotica (London. Print). 1997, Vol 27, Num 4, pp 379-387, issn 0049-8254Article

The demethylenation of methylenedioxymethamphetamine (ecstasy) by debrisoquine hydroxylase (CYP2D6)TUCKER, G. T; LENNARD, M. S; ELLIS, S. W et al.Biochemical pharmacology. 1994, Vol 47, Num 7, pp 1151-1156, issn 0006-2952Article

Transformation of dopamine and α-methyldopamine by NG108-15 cells : formation of thiol adductsPATEL, N; KUMAGAI, Y; UNGER, S. E et al.Chemical research in toxicology. 1991, Vol 4, Num 4, pp 421-426, issn 0893-228X, 6 p.Article

Mechanism-based inhibition of cytochrome P-450 by heterocyclic analogues of phencyclidineBRADY, J. F; DOKKO, J; DI STEFANO, E. W et al.Drug metabolism and disposition. 1987, Vol 15, Num 5, pp 648-652, issn 0090-9556Article

Interaction of xylamine with peripheral sympathetic neuronsRANSOM, R. W; WAGGAMAN, L. A; CHO, A. K et al.Life sciences (1973). 1985, Vol 37, Num 13, pp 1177-1182, issn 0024-3205Article

Role of superoxide in the N-oxidation of N-(2-methyl-1-phenyl-2-propyl)hydroxylamine by the rat liver cytochrome P-450 systemDUNCAN, J. D; DI STEFANO, E. W; MIWA, G. T et al.Biochemistry (Easton). 1985, Vol 24, Num 15, pp 4155-4161, issn 0006-2960Article

Oxidation of methamphetamine and methylenedioxymethamphetamine by CYP2D6LIN, L. Y; DI STEFANO, E. W; SCHMITZ, D. A et al.Drug metabolism and disposition. 1997, Vol 25, Num 9, pp 1059-1064, issn 0090-9556Article

Deamination of amphetamines by cytochromes P450 : Studies on substrate specificity and regioselectivity with microsomes and purified CYP2C subfamily isozymesYAMADA, H; SHIIYAMA, S; SOEJIMA-OHKUMA, T et al.Journal of toxicological sciences. 1997, Vol 22, Num 1, pp 65-73, issn 0388-1350Article

Participation of cytochrome P450-2B and -2D isozymes in the demethylenation of methylenedioxymethamphetamine enantiomers by ratsKUMAGAI, Y; LIN, L. Y; HIRATSUKA, A et al.Molecular pharmacology. 1994, Vol 45, Num 2, pp 359-365, issn 0026-895XArticle

A behavioral and pharmacokinetic study of the actions of phenylcyclohexyldiethylamine and its active metabolite, phenylcyclohexlyethylamineCHO, A. K; HIRAMATSU, M; SCHMITZ, D. A et al.The Journal of pharmacology and experimental therapeutics. 1993, Vol 264, Num 3, pp 1401-1405, issn 0022-3565Article

Determination of the mechanism of demethylenation of (methylenedioxy)phenyl compounds by cytochrome P450 using deuterium isotope effectsFUKUTO, J. M; KUMAGAI, Y; CHO, A. K et al.Journal of medicinal chemistry (Print). 1991, Vol 34, Num 9, pp 2871-2876, issn 0022-2623Article

Enantiomeric differences in the effects of 3,4-methylenedioxymethamphetamine on extracellular monoamines and metabolites in the striatum of freely-moving rats: an in vivo microdialysis studyHIRAMATSU, M; CHO, A. K.Neuropharmacology. 1990, Vol 29, Num 3, pp 269-275, issn 0028-3908Article

MK-801 ameliorates delayed amnesia, but potentiates acute amnesia induced by CONABESHIMA, T; YOSHIDA, S; MORINAKA, H et al.Neuroscience letters. 1990, Vol 108, Num 3, pp 321-327, issn 0304-3940Article

Mechanism of oxidation of N-hydroxyphentermine by superoxideFUKUTO, J. M; DI STEFANO, E. W; BURSTYN, J. N et al.Biochemistry (Easton). 1985, Vol 24, Num 15, pp 4161-4167, issn 0006-2960Article

Inactivation of constitutive hepatic cytochromes P450 by phencyclidine in the ratHIRATSUKA, A; CHU, T. Y. Y; DISTEFANO, E. W et al.Drug metabolism and disposition. 1995, Vol 23, Num 2, pp 201-206, issn 0090-9556Article

Enzymatic and chemical demethylenation of (methylenedioxy)amphetamine and (methylenedioxy)methamphtetamine by rat brain microsomesLIN, L. Y; KUMAGAI, Y; CHO, A. K et al.Chemical research in toxicology. 1992, Vol 5, Num 3, pp 401-406, issn 0893-228XArticle

Aromatic hydroxylation of methylenedioxybenzene (MDB) and methylenedioxymethamphetamine (MDMA) by rabbit liver microsomesKUMAGAI, Y; SCHMITZ, D. A; CHO, A. K et al.Xenobiotica (London. Print). 1992, Vol 22, Num 4, pp 395-403, issn 0049-8254Article

Hydroxyl radical mediated demthylenation of (methylenedioxy)phenyl compoundsKUMAGAI, Y; LIN, L. Y; SCHMITZ, D. A et al.Chemical research in toxicology. 1991, Vol 4, Num 3, pp 330-334, issn 0893-228X, 5 p.Article

Metabolism of methylenedioxyphenyl compounds by rabbit liver preparations : participation of different cytochrome P450 isozymes in the demethylenation reactionKUMAGAI, Y; WICKHAM, K. A; SCHMITZ, D. A et al.Biochemical pharmacology. 1991, Vol 42, Num 5, pp 1061-1067, issn 0006-2952Article